After graduating from MMC with a double major in Biology and Behavioral Neuroscience, Keaven Caro ’17 landed a job as a Research Assistant at the Friedman Brain Institute at the Icahn School of Medicine at Mount Sinai.
“My lab’s research project focuses on a protein called lynx1 and its role as a regulator of neuroplasticity during postnatal neural development. We are looking at its effects in top down neurons that project from the Anterior Cingulate Cortex to the visual cortex with respect to attention deficits in a mouse model. We are currently working on altering the levels of lynx1 in disease models that show attention deficits such as autistic Shank3 Knock out mice, in order to rescue their visual attention deficit.
I perform many aspects of the research, maintain the behavior room and equipment, and attend weekly lab meetings where I update the primary investigator and lab members on the progress of the behavioral experiments. The aspects of research that I conduct include: running mice through 5 choice serial reaction time task (behavior), perfusion of mice to preserve their brains, freezing preserved brains, coronal serial sectioning of preserved and frozen mouse brains at 35 and 60 microns, mounting brain sections on slides, imaging said slides on LSM 780 confocal microscope and Leica DMi8 brightfield microscope, validating brain images, piloting immunohistochemistry experiment, and updating behavior data on excel sheets. I will also begin training in surgeries to inject viral vectors that will alter the expression of lynx1 in the brains of mice in the near future.”
Location: 1470 Madison Avenue (Leon and Norma Hess Center for Science and Medicine) Friedman Brain Institute at the Icahn School of Medicine at Mount Sinai.
Class Year and Major
Class of 2017, Major in Biology and Behavioral Neuroscience